Speaker Biography

Biography:

Abstract:

Background: Osteonecrosis of the femoral head (ONFH) is a debilitating disease in orthopedics, frequently progressing to femoral head collapse and osteoarthritis. It is thought to be a multifactorial disease. ONFH ultimately results in femoral head collapse in 75-85% of untreated patients. Total hip arthroplasty yields satisfactory results in the treatment of the end stage of the disease in older patients. However, disease typically affects males between the ages of 20 and 40 years and joint replacement is not the ideal option for younger patients. Recently, mesenchymal stem cells and platelet rich plasma (PRP) have been used as an adjunct to core decompression to improve clinical success in the treatment of pre-collapse hips.

Materials and methods: A prospective study carried on 40 hips in 30 patients with a mean age 36.7±6.93 years. The indication for the operation was restricted primarily to modified Ficat Stages IIb and III. The average follow up was 41.4± 3.53 months.

Results: Harris Hip Score was improved from 46.0±78 preoperatively to 90.28±19at the end of follow up. The comparison between average scores showed statistical significant difference (p<0.0001). The average values of V.A.S. were 78 ± 21 and 35 ± 19 at pre and post-operative respectively with an average reduction of 43 points.

Conclusion: We found that the use of PRP with collagen sheet can increase the reparable capacity after drilling of necrotic segment in stage